Biochemical analysis department focuses on quality analysis and control of biopharmaceuticals. The Department is mainly responsible for the analysis and characterization of biological drugs, the structure and function research, the establishment of batch release standards and the establishment and validation of related biochemical analysis methods.
Biochemical analysis department has a high-quality and reasonable scientific research team. The scientific research personnel of the Department have the professional knowledge of Biochemistry, microbiology and analytical chemistry, and have rich experience in protein purification, drug analysis, mass spectrometry and other fields, which can ensure the smooth progress of the Department's projects. At the same time, the members of the Department carried out experiments in accordance with strict and standardized management system and standard operating procedures to ensure the accuracy of experimental data.
Advanced instruments and equipment
Invitrogen 2-D electrophoresis system
Bio rad 1-D electrophoresis system
GE AKTA purifier 100
Biacore (in collaboration with universities)
Bruker maldi-tof-tof (cooperation with universities)
Analysis and characterization of biological drugs
Disulfide bond localization
Identification of post translational modifications
Protein protein interaction
Biacore was used to study the interaction between proteins, which was mainly used in the determination of antibody affinity.
Qualitative analysis of proteomics mass spectrometry
The impurity bands of biopharmaceuticals in 2-D or 1-D SDS-PAGE electrophoresis were mainly identified by gel enzymolysis combined with MALDI-TOF.
Content determination of small molecular compounds
Determination of monosaccharide content
Determination of sialic acid content
Determination of amino acid content
Development and validation of biochemical analysis methodology
It is mainly responsible for the development and validation of quality standard methods for batch release of biopharmaceuticals, as well as the development of analytical methods of relevant departments.
* pat / QBD applied biopharmaceutical production
Pat / QBD technology is used to design the quality of biopharmaceuticals in the process of drug development and production, so as to ensure the quality controllability and safety of biopharmaceuticals.
Address: Building 7, Kangyuan medical science and Technology Park, 578 longmian Avenue, Jiangning District, Nanjing City, Jiangsu Province
Postal Code: 211100
Contact information: 025-58310595 (switchboard)